Nick Bostrom

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Far from being the smartest possible biological species, we are probably better thought of as the stupidest possible biological species capable of starting a technological civilization - a niche we filled because we got there first, not because we are in any sense optimally adapted to it

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Think of a "discovery" as an act that moves the arrival of information from a later point in time to an earlier time. The discovery's value does not equal the value of the information discovered but rather the value of having the information available earlier than it otherwise would have been. A scientist or a mathematician may show great skill by being the first to find a solution that has eluded many others; yet if the problem would soon have been solved anyway, then the work probably has not much benefited the world [unless having a solution even slightly sooner is immensely valuable or enables further important and urgent work]

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Our approach to existential risks cannot be one of trial-and-error. There is no opportunity to learn from errors. The reactive approach — see what happens, limit damages, and learn from experience — is unworkable. Rather, we must take a proactive approach. This requires foresight to anticipate new types of threats and a willingness to take decisive preventive action and to bear the costs (moral and economic) of such actions

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[D]umb evolutionary processes have dramatically amplified the intelligence in the human lineage even compared with our close relatives the great apes and our own humanoid ancestors; and there is no reason to suppose Homo sapiens to have reached the apex of cognitive effectiveness attainable in a biological system